ATG deserts define a novel core promoter subclass
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چکیده
منابع مشابه
Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression.
Functional analysis of naturally occurring hepatitis B virus (HBV) mutations is crucial in understanding their impact on disease. We have recently identified two mutations in the HBV core promoter of an HBV strain associated with fulminant hepatitis leading to highly (15-fold) enhanced replication as a result of increased viral encapsidation of pregenomic RNA into the core particles (T. F. Baum...
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DNA annotation is an important problem in molecular biology. The task in annotation is to detrmine functional roles of DNA regions. In this article, we are interested in core promoter regions in eukaryotes; these are approximately 50bp in length, and are believed to act as the critical factor in attracting the transcription initiation complex to the DNA at that Site, so promoting the transcript...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2005
ISSN: 1088-9051
DOI: 10.1101/gr.3873705